Lactate dehydrogenases in antarctic and temperate fish species

first_img1. The kinetics of lactate dehydrogenase (both forward and back reaction) in cardiac and skeletal muscle of an Antarctic teleost have been compared with a temperate teleost of comparable morphology and ecology.2. In both species the forward reaction (pyruvate to lactate) is maximally activated at 2.5–4 mM pyruvate and inhibited above this level.3. The Michaelis constant (Km) for pyruvate is not significantly different between muscle types or between species when measured at their normal environmental temperature.4. Km for pyruvate varies with temperature in a positive direction.5. The back reaction (lactate to pyruvate) is maximally activated by 12–16 mM lactate but only in skeletal muscle of the antarctic species is there inhibition above this level.6.6. The Km for lactate is significantly (P<0.05) lower in the Antarctic fish cardiac muscle.7.7. While the two species are morphologically and ecologically similar, differences at the biochemical level are discussed with respect to environmental temperature range and conservation of enzymic characteristics.last_img read more

A survey of natural electromagnetic noise in the frequency range f = 1–10 kHz at Halley station, Antarctica: 1. Radio atmospherics from lightning

first_imgThis paper presents results from the first systematic survey of VLF wave activity at Halley, Antarctica (76 °S, 27 °W, L = 4.3). Beginning in 1971, the peak, average and minimum (P, A, M) signal levels observed in four frequency bands centred on 0.75 kHz, 1.25 kHz, 3.2 kHz and 9.6 kHz have been recorded every 5 min. At these frequencies the observed radio noise is largely natural, the waves being generated either in the magnetosphere (e.g. chorus, hiss, etc.) or near the ground, the latter principally from lightning discharges (radio atmospherics, or “spherics”) which reach the receiver after propagating some distance in the Earth-ionosphere waveguide (lightning does not occur in the immediate vicinity of Halley). Here we analyse the observations for 1984, the first complete year for which we have data in digital form, in terms of thunderstorm regions, as a benchmark for more extended studies of possible long-term change in global lightning activity. The data are presented in compressed colour graphic format which facilitates the identification of periodic (diurnal and annual) and aperiodic variations. At 3.2 kHz, attenuation in the Earth-ionosphere waveguide is severe, and only relatively few spherics, from close lighting source regions, are observed. Thus, whilst the 3.2 M channel is insensitive to lightning, and responds mostly to magnetospheric emissions, the 3.2 P channel is dominated by spherics. The 3.2 P data show a marked diurnal and seasonal variation symmetrical about Halley local noon and about the solstices, consistent with nearby sources and attenuation rates for subionospheric propagation which are much greater during the day than at night. At 9.6 kHz, waveguide attenuation is much lower (and there is less difference between day and night), and the minimum channel is dominated by a continuum of spheric noise originating from globally distributed distant source regions, notably those in the tropics. Consequently, there is no control by the local dawn-dusk terminator; the diurnal and seasonal variation is not symmetrical about Halley local noon and the solstices but consists of a quasi-sinusoidal diurnal variation, in which the phases of the minimum and maximum vary during the year: ~07 LT (LT∼-UT−2h at Halley) and ~17 LT in December (summer) and ~10 LT and ~21 LT in June (winter). Agreement between the observations and the CCIR (1983) empirical model is poor. A somewhat better fit is given by a simple model in which thunderstorm regions consist of point sources having radiated powers which vary with local time and season, the total effect at Halley being modelled as the sum of contributions from these sources.last_img read more

Modification of deep waters in Marguerite Bay, western Antarctic Peninsula, caused by topographic overflows

first_imgCircumpolar Deep Water (CDW) intrudes from the mid-layers of the Antarctic Circumpolar Current onto the shelf of the western Antarctic Peninsula, providing a source of heat and nutrients to the regional ocean. It is well known that CDW is modified as it flows across the shelf, but the mechanisms responsible for this are not fully known. Here, data from underwater gliders with high spatial resolution are used to demonstrate the importance of detailed bathymetry in inducing multiple local mixing events. Clear evidence for overflows is observed in the glider data as water flows along a deep channel with multiple transverse ridges. The ridges block the densest waters, with overflowing water descending several hundred metres to fill subsequent basins. This vertical flow leads to entrainment of overlying colder and fresher water in localised mixing events. Initially this process leads to an increase in bottom temperatures due to the temperature maximum waters descending to greater depths. After several ridges, however, the mixing is sufficient to remove the temperature maximum completely and the entrainment of colder thermocline waters to depth reduces the bottom temperature, to approximately the same as in the source region of Marguerite Trough. Similarly, it is shown that deep waters of Palmer Deep are warmer than at the same depth at the shelf break. The exact details of the transformations observed are heavily dependent on the local bathymetry and water column structure, but glacially-carved troughs and shallow sills are a common feature of the bathymetry of polar shelves, and these types of processes may be a factor in determining the hydrographic conditions close to the coast across a wider area.last_img read more

‘Lost’ 175,000 Covid vendors return amid delayed Spring market

first_imgSome 175,000 missing vendors who would have sold their homes during the March, April and May lockdown have returned to the market, Rightmove has claimed.In an upbeat assessment of the post-lockdown housing market recovery, the portal also says the number of sales agreed has recovered from a 94% slump to being just 3% off pre-Covid levels, suggesting the delayed Spring market is now taking place.But the widely expected advent of price renegotiations including gazumping has also not materialised.  Buyers have agreed to pay 97.7% of asking price on average, up from February’s average of 96.6%.The renewed supply of properties being listed means it is now a buyer’s market and, Rightmove reasons, vendors who negotiate hard on price are seeing vendors reject offers.“There are no signs of panic selling or even a price dip,” says Miles Shipside, its housing market analyst.“Some sellers who had agreed a sale before lockdown have been worrying that their buyer may try to re-negotiate with a reduced offer. “On this evidence buyers may now be trying to exchange quickly, as there are signs of high pent-up demand and upwards price pressure, rather than downwards.”Rightmove suggests this mini-boom as some agents have been calling it, may continue throughout the summer as families who are unable to go on the traditional annual holiday concentrate on house moving instead.David Plumtree (left), Group Chief Executive of Connells, says: “There is strong demand from first time buyers despite a shortage of higher loan to value mortgage products.”  Rightmove Miles Shipside connells David Plumtree June 15, 2020Nigel LewisWhat’s your opinion? Cancel replyYou must be logged in to post a comment.Please note: This is a site for professional discussion. Comments will carry your full name and company.This site uses Akismet to reduce spam. Learn how your comment data is processed.Related articles BREAKING: Evictions paperwork must now include ‘breathing space’ scheme details30th April 2021 City dwellers most satisfied with where they live30th April 2021 Hong Kong remains most expensive city to rent with London in 4th place30th April 2021 Home » News » Housing Market » ‘Lost’ 175,000 Covid vendors return amid delayed Spring market previous nextHousing Market‘Lost’ 175,000 Covid vendors return amid delayed Spring marketStronger than expected return to a semblance of normality has also prevented price drops – agreed sales prices have risen to 97.7% of asking price.Nigel Lewis15th June 202001,158 Viewslast_img read more

Meet John Flood, Candidate for Ocean City Mayor

first_imgBy Donald WittkowskiJohn Flood is promising voters that he will have a transparent government, a stronger partnership with City Council and an open-door policy with the public in his campaign to become Ocean City’s next mayor.Born and raised in Ocean City, the 65-year-old Flood is stressing his family’s longtime ties to the resort town, his business experience and his years of public service as a former councilman and former member of the Library Board of Directors.In the weeks leading up to the May 8 mayoral election, he will discuss key issues and his campaign platform in a series of stories published in OCNJDaily.com.In this introductory story, he explains why he is running for mayor, changes he would make in City Hall if elected and his plan to build a friendlier relationship between local government and the public.Why are you running for mayor?Like most of the people, I’m very satisfied with the basic services our government provides us. Our town is a clean and safe community, with many sports and cultural opportunities for all ages. Our trash is collected and our Public Works employees do an excellent job. When someone calls 911, the police, fire or rescue personnel arrive quickly and are very professional. This praise should be attributed directly to the hard-working men and women of the city. Ocean City is truly a great place to live.However, I became complacent and lost touch with the way our government makes decisions. So, I began to look at how that decision-making process works and how our government is functioning and spending our tax dollars. I became concerned, and as I looked deeper, that concern grew.I’m running to inform the public of how our government makes those decisions and spends our money. It’s not working the way it was designed. All of the decisions should not be done by one person and then rubber-stamped by the City Council. You would be hard-pressed to find anything the mayor has taken to Council that wasn’t passed by a unanimous vote, let alone voted down. This lack of notice and transparency has to change.John Flood with his wife, Cathy, in a photo from his Facebook pageWhat have you learned while speaking to the public during your campaign?They say all politics are local. In the short time I have been talking to voters, many issues are neighborhood-specific. If you live in a flood-prone area, that’s the big issue. If your alley or street hasn’t been paved in years, that may be the one for that neighborhood.But many people seem to be frustrated with the lack of true transparency and getting answers to their concerns. Whether it’s not consulting the downtown merchants about the sidewalks on Asbury Avenue, the chopping down of the trees and growth on 52nd Street, or any other number of projects, people want to be informed beforehand. They want to be asked their opinion rather than being told this is how it’s going to be done.I’ve also heard from people who say, basically, eight years is enough.By far the most disturbing thing I’ve heard on the campaign trail – and I’ve gotten this from quite a few people – is their fear of retaliation if they don’t support the mayor. I heard this a lot from getting people to sign my petition or to put up my campaign signs.One person feared signing my petition would mean their son wouldn’t get a summer job with the city. A business owner said he didn’t sign it because he would lose business from some of the developers. It shouldn’t be that way.My only hope is that when people get into the privacy of the polling booth, they vote for fairness over fear. I think it was Thomas Jefferson who said, “When people fear their government, that’s tyranny. When the government fears the people, that’s liberty.”John Flood wants to have more transparency in city government and an open-door policy with residents.How would your administration be different than the current one?I’d want our city to treat all of the businesses and anybody who has business with the city the same, equally, and with respect. I would not take City Council, and their opinion, for granted. I would look for them to be a partner and allow them to do their job.I would also look to find new ways to use technology to better inform the people about future projects and current projects and to get their opinions prior to making a decision. One possibility is using the city website to post initiatives.There shouldn’t be any reason that we shouldn’t be able to post on our website that, within 30 days, an ordinance is going to be put up for consideration. This would be done by the administration.We’d post the ordinance online before presenting it to Council, giving people the ability to send in their comments. We can take those comments and potentially tweak the ordinance before it goes to Council, as opposed to the way it is now: The ordinance comes up for first reading and on second reading, somebody stands up and says something about it. Then the ordinance is either tabled or doesn’t get changed, or gets changed at the last minute without a thoughtful process about how that change would affect it.John Flood’s background:He was born and raised in Ocean City. He graduated from St. Augustine’s Grammar School in Ocean City and Ocean City High School. He has a bachelor’s degree in business from Jacksonville University.He and his wife, Cathy, have been married for 37 years. They have two grown children, Justin and Katie.He was a member of City Council from 1988 to 1996, representing the Third Ward. He served as Council president during three of those years. From 1997 to 2008, he served on the Library Board of Directors. As the board’s president, he oversaw major renovations to Ocean City Free Public Library and the Ocean City Community Center.His family roots in Ocean City date back about 100 years. His grandparents started Palmer Chevrolet and Oldsmobile in 1933. His parents started the Wash Bowl Coin-Op Laundry in 1959, which Flood later operated, as well as the 16th Street Car Wash.As a commercial real estate developer, Flood owns and manages properties that include offices for doctors, dentists and accountants. The CVS store on 16th Street, the Bacharach Ocean City Therapy Center, a car wash and a seasonal seafood restaurant are among the tenants in his development portfolio. Mayoral candidate John Flood oversaw major renovations to the Ocean City Free Public Library when he formerly served as president of the Library Board of Directors.last_img read more

Ocean City Library Expanding Hours

first_imgStarting in May, the library will be open during the week until 9 p.m. and on the weekends until 5 p.m. By MADDY VITALESince the pandemic, the Ocean City Free Public Library (OCFPL) has remained a center of activity, albeit through virtual means for programming, speedy curbside pickup and shortened library hours.But with the availability of the COVID-19 vaccines prompting more and more people to get vaccinated, the world appears to be opening up.On Monday during a Zoom meeting, the OCFPL Board of Trustees announced that after a year of abbreviated hours of operation, the library will be staying open longer beginning on May 10.The expanded library hours are as follows: Monday through Friday from 10 a.m. to 9 p.m., Saturday from 10 a.m. to 5 p.m. and Sunday from 11 a.m. to 5 p.m. Curbside hours will continue.OCFPL Director Karen Mahar explained that in keeping with strict health and safety protocols, employees will spend an hour sanitizing and preparing the library to open for patrons each morning.Mahar said that both she and her management staff are “all on board” with the longer hours of operation.“We feel it is time and we are ready,” she said. “I know the administration and the city would like to see that, too.”She added that the library has complied with the governor’s capacity limits and remains under the allowable number of people in the building at any given time.“We increased the number of people to 100 in the library – not the maximum of 35 percent,” Mahar said of the allowable limits.While people can come in and select their items, there will still be a host of virtual programming.Mahar added that patrons do not stay long and just come in to get their books and other resources before leaving.Despite the extension of hours, she noted that there will not be in-person programming allowed anytime soon, given the current capacity limits.However, virtual programming, which has been a popular attraction at the library throughout the pandemic, will continue into the foreseeable future, she said.“We will still continue all of our virtual programming, which we feel is a huge success,” Mahar said. “We get hundreds of people in our programs.”In other matters, the renovation grant for the library’s second floor was a topic of discussion.Mahar announced that the library, with the assistance of the city, will resubmit for a grant through the state Library Bond Construction Act.The grant would help fund the library’s estimated $1.3 million renovation project on the second floor.Back in December 2020, Mahar announced that the grant proposal submitted by the city for the money was not approved.“The first round of the Library Bond Construction Act grant awardees came out and we were not on the list,” she had said.The city had already bonded for the project to renovate, update and expand the library’s second floor and it will be done with or without the grants, officials have emphasized.The building is over 30 years old. Here is a link to the project’s rendering: https://ocnjdaily.com/wp-content/uploads/2018/08/library-renovation-rendering-2.pdfThe second round of grant applications is due into the state the first week of June.Vince Bekier, the city’s director of operations and engineering, and Rachel Ballezzi, also of the engineering department, will resubmit the grant proposal to the state library, Mahar said.“We will be resubmitting the grant proposal then,” Mahar said. “There is the second round now and we were able to apply for it.”For more information about the Ocean City Free Public Library, visit www.oceancitylibrary.orgThe library is located in the Community Center at 1735 Simpson Ave.last_img read more

Kerrs to open new £1m bakery

first_imgKerrs Bakery is celebrating its 10th anniversary by opening a new £1m factory in Motherwell, with annual turnover predic- ted to reach more than £2m this year. The new factory is three times the size of the old one and Kerrs expect to hire an additional 13 staff, to join its existing team of 20, before the summer.The wholesale business – one of the main producers of Caramel Cake in Scotland – manufactures a wide range of long-life handmade cakes, as well as short- life cakes with a 12- to 14-day shelf-life.Founder Karen Murray opened a small shop in Armadale, West Lothian, 10 years ago with start-up help from the Prince’s Scottish Youth Business Trust, to make caramel cake. Products are distributed directly to small grocers, coffee shops, delicatessens and supermarkets, mainly in Scotland, and Murray has plans to expand the retail supply. “We have done some small orders for Scottish supermarkets and would like to develop that this year,” she said.last_img read more

Speech: Home Secretary Police Superintendents’ Conference speech 2018

first_imgI’m delighted to be here today at the Police Superintendents’ Association’s Annual Conference.Now before I say anything else I know what you are thinking. Let me say right from the start, I am watching The Bodyguard.I am not happy about what happened to the Home Secretary in the last episode.Also, my codename is not Lavender.I’m probably feeling a lot more nervous than the Prime Minister Theresa May did when she spoke at this conference 3 years ago.And that’s because I know that I have at least one guaranteed critic in the audience.And that’s my brother.He’ll be watching my every move and listening to every word I say.I’m sure as soon as I’ve got out of here and in my car my phone will ring and he’ll tell me all the things about what I’ve said and things like that.Or he’ll just say I should have worn a better suit!Mind you, I probably should take it on the chin given I’m responsible for thousands of journalists now following him on Twitter.The combination of being Home Secretary and having a Chief Superintendent as a brother, has taught me a lot about what it means to be a Police Super.I know what an important role you play each and every day managing frontline officers.I know how hard you all work coming up with the strategic direction for your forces.And I know how much effort you have to put in every day to fight crime in your communities.The Police Superintendents’ Association is a very valued government partner.And I’m very sorry that this conference will be the last Gavin will attend.Since he took over the presidency in 2016, his dedication, passion and commitment have been really impressive and we will all be really sorry to see him go.The association provides constructive advice to the government and it is a powerful force for change.We haven’t always agreed in the past, and of course we won’t always agree in the future.But what I appreciate most about the Police Superintendents’ Association, is the willingness to have conversations with government.Conversations about how to improve policing and make things better.And that’s what I want to talk to you about today – my view on how we can work together to improve policing.Because even though I think my outlook for policing is a bit more optimistic than Gavin’s, I know that improvements have to be made.Many of you will be aware of the National Audit Office report on police financial sustainability today.And whilst there are a number of aspects of the report that I don’t quite agree with, it rightly recognises the pressures on the police.When I stood up at the Police Federation conference in May, I said that I will stand with the frontline.That I will do all I can to support your teams.And that I will listen to the police.It is these 3 principles:Standing with you.Supporting you.And listening to you – that informs every single decision I make about policing as Home Secretary.You’ve been telling me that you and your forces are feeling stretched.That the nature of crime is changing and that sometimes you feel that you just can’t keep up with it.We know that so-called ‘traditional crime’ is down by a third since 2010.But that there are all sorts of other crimes which are being reported more than ever before and putting demands on policing.Like hate crime and child sexual abuse.The threat from terrorism we’ve sadly seen has also escalated and evolved.And we also know that you are now more likely to be the victim of crime online than offline.There has also been a recent increase sadly in serious violence – including homicides, knife and gun crime.But from all sides, the clamours from the press, politicians from all parties and the public seem to be for you to do “more, and do more, and do more”.And as superintendents, you sometimes feel like you’re being pulled in all sorts of different strategic directions.You’re having to change the strategic direction of your forces to manage new and emerging threats and to adapt your resources accordingly.I want you to feel that you are comfortably equipped to deal with the changing crime landscape.And yes, part of it is of course resources.That’s why we’re now investing over £1 billion more in policing than we did 3 years ago, including more money raised through council tax.That’s why just last week; I announced a £21 million extra to help law enforcement agencies to help fight online child sexual exploitation.That’s why as a government we put over £50 million over the next year to boost cyber capabilities within law enforcement at a national, regional and local level.We’re also making £40 million available over the next 2 years to help support the new Serious Violence Strategy.Despite this increase in funding, I do recognise the pressures on policing.Let me be clear with you, I will continue to fight on the police’s behalf to ensure you have the resources you need to do your jobs effectively.But making sure that forces are fit for the future isn’t just about the finances.You also need to have the tools and support to do your jobs.Firstly, I think it’s vital that you get the training you’ve asked for.As Gavin has already said, those of you who work in Public Protection Units sometimes feel like you’re thrown in at the deep end without having that necessary training and support.And as we’ve just heard the truly shocking stat that 87% of those leading units to protect children receive no training or development for the role.This needs to change.I fully support the work the College of Policing is doing to develop a public protection learning programme.And my department continues to assist the College to develop the Licence to Practise Scheme for people who are working in these high risk areas.This should mean that no one is put in a position where they’re being asked to take on vital public protection roles without adequate preparation.Secondly, you and the men and women that work for you, you need the right powers.One of these powers, for example is Stop and Search.I am consulting on extending Stop and Search so that officers are able to stop and search anyone suspected of carrying acid without good reason.We all remember the case just a few weeks ago of the 3 year-old boy who was seriously hurt when he was the target – a 3 year-old boy, a target – of an acid attack in Worcester.A month before that, 2 teenage victims were taken to hospital in East London after they were sprayed in the face.Criminals cannot feel they can walk around our streets carrying dangerous weapons and get away with it.The men and women who work for you need to feel comfortable and supported when they are using Stop and Search.As I’ve said before, the evidence shows that if you’re black you’re more likely to be a homicide victim than any other ethnic group.If Stop and Search mean that lives can be saved from the communities most affected, then of course it’s a very good thing.And as senior leaders, I want you to support frontline officers to ensure they’re confident in using this important power.Thirdly, you need to feel like you’re being rewarded for the work that you do.I know that some of you feel like the roles that you currently have, have morphed over time and that the job you now do doesn’t resemble the job you originally signed up to do many years ago.Perhaps the area you cover has got larger, or the number of people you manage has gone up?Maybe what you’re being asked to deal with an issue that is particularly challenging without getting all those resources and the support you need?The National Police Chiefs Council has submitted proposals which would allow chief constables to give a discretionary bonus payment of up to £4,000 a year for officers who take on those hard to fill roles and superintendents with especially challenging roles.And today I can announce that I offer my full support to these proposals and that I intend to legislate so these bonuses can be given out.I can also confirm that chief constables will be able to authorise these payments to be backdated to 1 September 2017.Fourthly, you need to feel like your welfare is being taken seriously.I was disgusted to see a recent video on social media of police officers being kicked from behind on the floor in a McDonalds restaurant.Being beaten up should never be a part, or considered to be part, in any way, of the job.And I am in no doubt that those who assault police officers deserve to face serious consequences.That’s why I support the Assaults on Emergency Workers Bill which doubles the penalty available for low level assaults on police officers.The bill will receive royal assent this week and sends a clear message that attacks on public sector emergency workers will not be tolerated.At the Police Federation Conference, your teams also told me that they want better protection in the form of tasers and spit and bite guards.I’ve now written to police chiefs across the country stressing the importance of both of these.But it’s not just your physical welfare that we need to be thinking about.It’s mental health too.The association’s most recent resilience survey showed that half of respondents reported feelings of anxiety.As I made clear at the Police Federation Conference, I want us to work together to totally transform the welfare provision for policing.We’ve already pledged £7.5 million for a new national police welfare service.And today I’m pleased to announce that £400,000 of this money will be used to support the proposal by Chief Constable Andy Rhodes and the College of Policing, to get a new wellbeing outreach prevention service on the road next month.The first of a fleet of the so-called ‘wellbeing buses’ will be pulling up outside police stations and providing accessible, stigma-free support and information for anyone who feels they needs it.But I know that sometimes for you as leaders, it can be hard to ask for help.You might be good at signposting support services for others, and yet not very good at taking up the offer yourself.I urge you all to take advantage of the services now being offered.Finally, and most importantly, I want you to know that I will listen to you.The Frontline Review is now underway and I want to encourage you all to take part and to tell us about your experiences in policing.The Policing Minister Nick Hurd has been leading this important work and I know a group of you put your questions to him earlier today.There are lots of different ways you can get involved.From face-to-face discussions to online conversations.In fact, the Home Office’s first Twitter session caught the attention of over 40,000 people, and we had some 500 comments within the first hour.So it’s clear that there is a lot to say.But I don’t want you to leave it up to others to get involved.As Supers, you’re making decisions on behalf of your forces every single day.And I would love you to be more involved. You get a very different sort of insight to that of your colleagues, and I want to hear what you all think too.So if there’s one message I want to leave you with today, then it’s this.When you speak, I will listen.The Police Superintendents’ Association is a great force for good.You are tireless advocates for Police Superintendents and you’ve played a vital role in developing policing.I want this to continue long into the future.And my door will always be open to you.Thank you.last_img read more

Dave Matthews To Voice Bartender On New Episode Of ‘The Simpsons’

first_imgSunday night’s new episode of The Simpsons will feature a familiar voice actor: Dave Matthews.In the all-new episode, titled “Girls In The Band,” Matthews will (appropriately) voice a bartender. Mathews’ appearance on The Simpsons was announced via Dave Matthews Band social media channels on Sunday afternoon.You can watch Dave Matthews as “the bartender” on The Simpsons on FOX at 8/7c. Tune in or set your DVR to hear Dave chop it up with Homer Simpson from behind the bar. While you wait, you can watch this…Dave Matthews & Tim Reynolds – “Bartender” – Live at Radio City Music Hall[Video: FiftyFive]Dave Matthews has a busy tour schedule lined up for this coming spring and summer. Following his ongoing European run, Matthews will head back to the states for an extensive summer tour including appearances at high-profile festivals like New Orleans Jazz & Heritage Festival, KAABOO Del Mar, Something In The Water, Beale Street Music Festival, Sea.Hear.Now, and more.For a full list of Dave Matthews’ upcoming tour dates, head to his website here.last_img read more

Obamacare’s point guard: A parley with DeParle

first_img Read Full Story Nancy-Ann DeParle ’83, whose nearly four years in the Obama White House included serving as deputy chief of staff for policy until this past January, is best known for her role in the passage of the Patient Protection and Affordable Care Act, better known as Obamacare. As director of the White House Office of Health Reform from 2009 to 2011, DeParle was instrumental in the enactment and implementation of that historic legislation.During the spring semester, DeParle, a health policy expert who previously served in the Clinton administration, was a lecturer in law at HLS, co-teaching with Cass Sunstein the seminar Selected Problems in Regulatory Policy. She is also a guest scholar in economic studies at the Brookings Institution in Washington, D.C.Bulletin: Do you see the passage of the Affordable Care Act as a pivotal moment in American history?DeParle: I do—this is something that presidents of both parties, going back to President Theodore Roosevelt, have tried to achieve for our country. It fills a gaping hole in our social safety net by providing universal access to affordable health coverage, and it does it in a uniquely American way: requiring personal responsibility and building on private and employer-based markets. Now, all Americans will have health security, even if they lose their jobs or get sick.Read the rest of the interview on the Harvard Law School website.last_img read more