Mondays are usually a relatively low day for the number of cases reported, as states are still noting results from testing that took place over the weekend when many facilities are closed. But this Monday, the United States still notched up 127,000 additional confirmed cases of COVID-19. A week earlier, that would have been a record high. It’s also almost 40,000 cases higher than were reported the previous Monday. At the rate cases are soaring, it seems certain the United States will pass 150,000 cases in a single day at some point this week.This latest surge of virus continues to be extremely broad based. Both Illinois and Texas exceeded 10,000 new cases on Monday. Already on Tuesday, Illinois has announced 12,623 new cases, obliterating the state’s past record. It’s actually the highest value that any state has posted since Florida and Texas soared back in July, and higher than any daily number posted by New York in the opening phase of the pandemic (though limited testing at the time meant that cases in New York were badly underreported). An astounding 17 states reported over 3,000 new cases on Monday.- Advertisement – However, Pfizer’s vaccine announcement is genuinely good news. And it’s not just good news for Pfizer’s vaccine, or even just good news for COVID-19.The Pfizer vaccine’s high efficacy is fantastic news, because the vaccine targets the spike protein that COVID-19 uses to attach to human cells. The other “big four” vaccines now in Phase 3: Oxford / AstraZeneca, Moderna, and Johnson & Johnson also target that same protein. That means the world is likely to have a variety of effective vaccines, some of which may be easier to administer and easier to use in areas without extreme refrigeration.Pfizer’s vaccine is the first phase 3 trial of a vaccine using mRNA in a human. If the safety data holds up, the technology could potentially become a new standard in how vaccines can be rapidly developed against other diseases.Moderna’s vaccine is also mRNA based. Unlike Pfizer, they’re a relatively small company that has essentially bet the farm on this trial. They should be reporting their Phase 3 results within the next two weeks.Johnson & Johnson’s vaccine has some advantages in that it’s a single dose and doesn’t need temperatures lower than those provided by normal refrigerators. Their single dose approach means they should move through Phase 3 more quickly. However, they were the last of the major trials to begin, and they’re recruiting a large pool, so don’t expect results for another month or more.And of course, the best news possible is that it won’t be Donald Trump who handles the deployment of these vaccines. This isn’t Biden’s first experience in crisis management. After all, he walked into the White House in 2009 in the midst of the Great Recession and took charge of Obama’s response to that crisis. He’s used to managing large teams in dire circumstances. – Advertisement – Just a few points out of the morass of statistics: Illinois now has 4,742 people in the hospital with COVID-19, with 911 in the ICU, and 399 on ventilators. In North Dakota, 7.4% of the total population has now tested positive for COVID-19. Tennessee had as many cases in the last two days, as it had in the entire pandemic up until mid-June.Over time, the case fatality rate for new patients has decreased. But, so far at least, it’s hard to point at any miracle drug that accounts for this change. Trump’s much promoted hydroxychloroquine was never more than a pipe dream. Remdesivir, which seemed to represent a net positive for patients in mid-disease and gained FDA approval, has turned out to show no real effect in the largest trial to date. The only real advances seem to be in the use of anti-inflammatory steroids with patients who need supplemental oxygen or ventilation. If there’s any good thing at all to come from the pandemic so far, it may be that doctors have acquired a better understanding of how to conduct long period intubation while decreasing damage and lowering the rate of death—for the awful reason that they’ve had so many patients on which to test different procedures.Synthetic monoclonal antibody treatments, such as the Regeneron treatment given to Trump during his bout with the disease, do hold out a lot of hope for effective treatment. On Tuesday, Eli Lilly gained emergency approval for it’s version of a two-antibody cocktail, bamlanivimab. However, at the moment there are very few doses available. The total output of both Eli Lilly and Regeneron to date would not be enough to treat the positive patients of a single day at this point, and since the treatments are most effective when administered early, they’re not really a significant effect on the total national picture—even if they are of powerful net benefit for those patients lucky enough to receive one of these rare treatments. – Advertisement – – Advertisement – Now we just have to survive until vaccines, and Biden, arrive.
May 14, 2009 (CIDRAP News) – An international group of experts has examined and rejected the idea proposed recently by an Australian scientist that the novel H1N1 influenza (swine flu) virus is the product of a laboratory accident, the World Health Organization (WHO) reported today.”The group of scientists feels that this hypothesis does not really stand up to scrutiny, that the evidence suggests that this is a naturally derived virus, and not a laboratory-derived virus,” said Dr. Keiji Fukuda, WHO assistant director-general for health security and environment, at a press briefing today.Adrian Gibbs, 75, a veteran flu researcher, said recently that he had concluded from his analysis of the virus’s genetic sequence that it might have evolved in eggs used by scientists to grow viruses and by drug companies to make flu vaccines. Gibbs said he intended to publish a scientific paper describing his hypothesis, according to a May 13 Bloomberg News report.Fukuda said Gibbs contacted the WHO May 9 to communicate his idea, which he had arrived at by studying genetic data deposited in public databases, not from studying the virus directly.”Because of the nature of the hypothesis and the credible nature of the scientist, we took this seriously,” Fukuda said. The Bloomberg story said Gibbs was involved in research that led to the development of oseltamivir (Tamiflu).After hearing Gibbs’ idea, the WHO asked five of its collaborating centers to evaluate it, Fukuda said. A day later the agency asked the United Nations Food and Agriculture Organization (FAO) and the World Organization for Animal Health (OIE) to do the same. WHO officials discussed the hypothesis with a large group of experts in both human and animal influenza 2 days ago, he said. They concluded that Gibb’s proposition didn’t fit the evidence.Fukuda added that the WHO will need to review Gibbs’s research article when it is published, but he indicated that it is unlikely to change the experts’ conclusions.He cited the episode as a positive example of rapid, open scientific communication and debate on medical issues, facilitated by putting genetic data in public repositories.”We live in an age when it’s really not possible to hide things,” he said. “It’s all for the better as far as I’m concerned. Maybe it means a little more work, but you can also address it in a way which is convincing to people.””This is much better than dealing with rumors in which the basis for the rumor is not clear and then dealing with answers in which the basis of the answer is not clear,” he added.In response to a question, Fukuda said Gibbs suggested that the novel virus seems to have an increase in lysine (an amino acid) residues and that it sits out on a “long branch” of the influenza phylogenetic tree in comparison with other swine flu viruses. He said it is known that growing flu viruses in eggs can lead to an increase in lysine residues.However, human, avian, and swine flu viruses differ somewhat in this respect, Fukuda said, adding, “After discussion and looking at older swine influenza viruses, it was concluded that the amount of lysine being seen was in fact very consistent with the natural increase in lysine being seen in swine flu viruses.”Also, the experts who evaluated the hypothesis said that because of historical gaps in swine flu genetic data, many swine flu viruses are somewhat isolated on the phylogenetic tree, so Gibbs’ observation on this point was nothing unusual, according to Fukuda.In other comments at today’s briefing, WHO spokesman Gregory Hartl announced that the agency’s daily briefings would be suspended for about a week because of upcoming WHO meetings.A WHO-hosted intergovernmental meeting on virus sharing will begin tomorrow, Hartl said. That will be followed by the World Health Assembly, the annual meeting of WHO member countries, which runs all of next week.The intergovernmental meeting will deal with the sharing of viral isolates and access to vaccines and other products derived from them, an issue pursued by Indonesia in relation to H5N1 avian flu in recent years.In other comments at today’s briefing:Fukuda said experts who met today to discuss whether to recommend mass production of a vaccine for the novel H1N1 virus will probably need to meet several more times before they can come to a conclusion.He said the WHO has not seen any evidence that the novel virus is resistant to the antiviral drugs in use (oseltamivir and zanamivir), and the agency is not making any changes in its recommendations on antiviral use.The WHO continues to be concerned about the fact that most of the people infected with the H1N1 virus have been young, he said. About half of those who died were healthy and had no predisposing conditions. “It’s highly unusual for young, healthy people to die from influenza,” he said. “So this is a pattern which is different than what we see with normal influenza,” though it has been seen in previous pandemics.
Judges at the Simalungun District Court in North Sumatra have sentenced Gernal Luncu Nainggolan to one year in prison after he was found guilty of insulting Prophet Muhammad on Facebook.The verdict hearing took place on Oct. 8. The sentence was lighter than the initial punishment demanded by prosecutors of 1.5 years’ imprisonment.Presiding judge A. Hadi Nasution said the judges opted for a lighter sentence as Gernal had apologized for his mistakes. Both the defendant and prosecutors accepted the verdict and decided not to file an appeal.Read also: Medan YouTuber sentenced to prison for insulting Prophet Muhammad’s wife in a viral videoSimalungun Prosecutor’s Office intelligence unit head Ratno Timur Habeahan told The Jakarta Post on Tuesday that prosecutors decided to accept the verdict because the sentence still fulfilled two-thirds of the initial sentence demand.He added the prosecutors were still waiting to receive a copy of the verdict before transferring Gernal to a penitentiary, with the defendant sent to the Pematang Siantar detention center in the meantime.Gernal was found guilty of violating articles 45A and 28 of the 2016 Electronic Information and Transactions Law on inciting hatred on the basis of ethnicity, religion or race. He was reported to the authorities for a Facebook post that allegedly insulted Prophet Muhammad.He also mentioned controversial cleric Bahar bin Ali bin Smith in another post in May.Officers from the Simalungun Police arrested Gernal on May 21. He pleaded guilty and apologized for actions upon his arrest. (ami)Topics :
5 Fryer St, North WardPERFECTLY positioned on Melton Hill complete with a basketball court and pool that cascades down the side of the house lies this luxurious residence.5 Fryer St in North Ward has six bedrooms and four bathrooms and will be sold under the hammer on March 13. 5 Fryer St, North Ward 5 Fryer St, North Ward“There has been a lot of interest in this property and with the improvement in the high-market there is new confidence around.“The sellers are looking to move on so I think for the luxury market this will represent amazing value.” ■ 5 Fryer St will be open for inspection on Sunday from 9.30am to 10am. For more details call Ms Mahoney on 0428 242 817. 5 Fryer St, North WardMore from news01:21Buyer demand explodes in Townsville’s 2019 flood-affected suburbs12 Sep 202001:21‘Giant surge’ in new home sales lifts Townsville property market10 Sep 2020 5 Fryer St, North Ward 5 Fryer St, North WardThe house is on a 848sq m block with stunning views The white exterior contrasted against the aqua pool and basketball court gives the home a distinct coastal vibe which continues inside with timber flooring and a neutral colour palette.Ray White selling agent Julie Mahoney said it was one of Townsville’s most spectacular homes.“You can see the pool from the kitchen and lounge room – then you also have beautiful undercover deck areas with palazzo tiles and the kitchen is granite so everything is just top-notch,” she said.“This property is unique because to get a modern build in North Ward you really have to go up the top of the hill but with this house you walk down your driveway and you’re at the The Strand.
More from news02:37International architect Desmond Brooks selling luxury beach villa17 hours ago02:37Gold Coast property: Sovereign Islands mega mansion hits market with $16m price tag2 days agoSerenity Cove, Gold Coast.The sales splurge has prompted the Malaysia-based developers Sime Darby and Brunsfield International Group to bring forward the construction of a further 18 lots, with 15 expressions of interest already recorded.Savills director of residential Chris Jones said contracts were already being finalised.“We have noticed many purchasers relocating from other masterplanned communities within the area,” Mr Jones said.“Many have been attracted by Serenity’s low body corporate fees which are currently set at just $28 per week. The project has attracted professionals from Sanctuary Cove, Ephraim Island and Hope Island Resort, with most buyers appreciating the central location, less traffic and proximity to Paradise Point.”The new release is a mix of waterfront and dry lots, with some blocks featuring views over Coombabah Creek. The estate is designed to be a boating haven, offering direct access to Coomera River, the Broadwater and Coombabah environmental reserve. A $5 million lock links to the waterways for vessels up to 13m long and 4m wide. There will be a marina precinct with 3800sq m of retail and dining space fronting Lake Serenity.Mr Jones said Serenity Cove had attracted leading builders McCarthy Homes, Metricon, Clarendon Homes, Resolve Constructions and GJ Gardner Homes. The first residents have already moved in and seven homes are now under construction. Most buyers have been local owner-occupiers.Mr Jones said the new Hope Island Marketplace, which is just a two-minute drive away and scheduled to open in December, was also an attraction. Serenity Cove, Hope Island aerialA buyers’ spending spree at a masterplanned community on the Gold Coast has prompted the developers to fast-track the latest land release.Up to $16 million in land across 19 lots has been snapped up by buyers in just nine weeks at Serenity Cove, a $650 million gated community at Hope Island.
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Press Association Newcastle ensured Premier League survival with a game to spare as a 2-1 win saw already-relegated QPR go down with a whimper at Loftus Road. Hatem Ben Arfa’s penalty and a Yoan Gouffran strike helped the Magpies come from behind to secure a victory that ensured another season in the top flight despite the late sending-off of goalkeeper Rob Elliott. It had not always looked so plain sailing, though, with Loic Remy’s early spot-kick putting Harry Redknapp’s side ahead and ending a 376-minute wait for a goal. QPR edged a poor opening that only came into life in the 11th minute when Mathieu Debuchy gave away a penalty as referee Lee Probert adjudged him to have fouled Junior Hoilett. Yohan Cabaye was booked for his remonstrations but they counted for nothing, with former Newcastle target Remy slotting home. Ben Arfa burst into the box and Jose Bosingwa foolishly tugged the Newcastle man’s shirt in clear view of Probert. Another spot-kick was awarded and the France international stepped up to smash home, with the ball going in off the underside of the bar. It took just seven minutes for the Magpies to draw level and it appeared they had turned the match on its head by the 22nd minute. Debuchy swung in an exquisite right-wing cross that was nodded home at the far post by Papiss Cisse, only for the goal to be chalked off after the Senegalese striker drifted offside. Hoilett forced Elliott into a fine reaction save when QPR returned to the attack but, like so many times this season, poor-decision making cost them dearly. Bosingwa’s popularity plummeted to a new low after sending a weak back-pass to Rob Green and, under pressure from Jonas Gutierrez, the Rs goalkeeper could only clear as far as the unmarked Gouffran, who cushioned a volley into the empty goal. Newcastle were living dangerously with a one-goal lead – something that looked even more tentative eight minutes from time when they were reduced to 10 men. Goalkeeper Elliott handled the ball outside the box and was shown his second yellow of the afternoon, with Steve Harper replacing Ben Arfa for the closing stages.
Press Association The former Lyon and Marseille man is keen to showcase his talents once more, but would be keen on remaining on Tyneside even if he is not playing. “I don’t know why I’m not playing,” Ben Arfa told the Daily Mail. “You have to ask the manager. After the (4-0) defeat against Manchester United, we had a strong exchange of words, but that is it. “He doesn’t want me to play. I respect it. If he wants, I will play. I’m here for the club. I enjoy training. I just want to play. I’m fit. “If the manager says to me he doesn’t believe in me for next season, I want to stay, but if the chairman wants to sell me I have to go. I want to stay here even if the manager doesn’t believe in me because I will show him I can play here.” The Magpies could do with having Ben Arfa back to his best, having lost their last six Barclays Premier League matches, with the mood among the Toon faithful turning ever more sour towards Pardew. “We have lost too many times, 3-0, 4-0, 3-0. It is hard when you love the supporters, it is hard to lose every time like that,” Ben Arfa added. “On the pitch I can offer my flair and my creativity. I try every time to do something. I think I can give a lot for the club.” Hatem Ben Arfa is desperate to remain with Newcastle even if he continues to remain out of favour with manager Alan Pardew. The French playmaker has proved on numerous occasions in the past that he is capable of swinging a game in Newcastle’s favour, but injuries and a lack of fitness have combined to keep him on the fringes of the side this season. Ben Arfa admitted he had a frank exchange with Pardew following the 4-0 humbling by Manchester United on April 5, while it has been reported he was made to train with the reserves last week and was left out of the squad altogether for the 3-0 defeat at Arsenal on Monday.
Hull City rounded off their preparations for a first European campaign with a 1-1 draw against Barnsley at Oakwell in a game where goalkeeping errors led to both goals. Shane Long put the Premier League side in front three minutes into the second half, charging down Adam Davies’ clearance, but their hosts equalised on the hour when goalkeeper Eldin Jakupovic r ushed out to try to head clear a long ball from Dale Jennings only for the ball to bounce over his head for Barnsley’s new signing Connor Hourihane to slot into an empty net. Hull’s next match is their Europa League third qualifying round first leg against Trencin in Slovakia on Thursday. Burnley needed a 71st-minute goal from Jason Gilchrist to earn them a 1-0 win over League Two neighbours Accrington. QPR ended their tour of Germany with a 2-0 defeat by Red Bull Leipzig at Stadion Der Freundschaft. Rio Ferdinand and Steven Caulker made their debuts for Harry Redknapp’s men and trialist Jack Collison was also given a run-out but two second-half goals from Yussuf Poulsen proved to be the difference. West Ham United will return home empty-handed from their pre-season tour of New Zealand after losing 3-1 to A-League side Sydney FC in Wellington. Sam Allardyce’s side were 2-0 down at half-time before wideman Matt Jarvis saw his left-wing cross deflect off Sydney captain Nikola Petkovic and into the net five minutes after the restart. Sydney added a controversial third 18 minutes into the second half when Corey Gameiro capitalised on a missed handball to slot home his second of the game. It was West Ham’s second loss in three days after they were beaten 2-1 by Wellington Phoenix in Auckland on Wednesday. Arsenal suffered a 1-0 defeat against the New York Red Bulls at the Red Bull Arena in Harrison in a match featuring former Gunners favourite Thierry Henry for the opposition. Arsene Wenger fielded a strong Arsenal starting line-up but they fell behind to a Bradley Wright-Phillips opener just after the half-hour mark as he slotted home after Ambroise Oyongo headed down Henry’s corner. Jack Wilshere came close to netting an equaliser minutes later with a great effort on target, but the England midfielder was denied by goalkeeper Luis Robles. And Arsenal’s best chance to get something from this pre-season friendly came from 18-year-old striker Chuba Akpom in the second half, as he managed to shake of his marker, but then shot straight at Robles as the Gunners were denied in front of a crowd of 25,219. Press Association
“I can’t couldn’t be happier with the horse. We always thought he was better on nice ground, though he has won on heavy and on soft. He actually won a hurdle race there on heavy,” said Nash. “He had his last couple of bits or work at the weekend and he had a jump this morning and he couldn’t be in better shape, so I’m really looking forward to it. Hopefully, the meeting will be on. “He’s going there at least as well as last year, if not a bit better, so it’s fingers crossed. “Katie’s back on again tomorrow – we couldn’t take her off him! They got on so well last year and he’s got a grand weight of 10st 10lb. “Ground will obviously be an issue but I’d say it will be an issue for a lot of them, but as far as our horse is concerned I couldn’t be happier.” Owner JP McManus has four representatives, each one with a different trainer – Charles Byrnes’ Shanpallas, Enda Bolger’s Colour Squadron, Philip Dempsey’s Jacksonslady and British raider Cantlow, from Paul Webber’s stable. “Shanpallas ran a good race in the Galway Plate. He’d prefer a bit drier ground, but he’s in good form and we’re hoping for the best,” said McManus’ racing manager Frank Berry. “Jacksonslady got knocked about a bit in the Plate, had a rough passage and has come back well now. Although meetings on Monday and Tuesday had to be abandoned due to waterlogging, day three of the Harvest Festival looks set to go ahead after the course was declared fit for racing on Tuesday afternoon and Nash reports his 12-year-old to be in top form as he attempts to complete back-to-back victories in the three-mile showpiece. Katie Walsh, who partnered Your Busy to a half-length triumph over Pass the Hat 12 months ago, will be back on aboard the gelding for the first time since then. Owner-trainer James Nash is looking forward to Your Busy putting up a strong defence of his crown in the Guinness Kerry National at Listowel on Wednesday. “Cantlow didn’t make the cut in the Plate and was a little bit disappointing over hurdles that day, but he’s back in good form and hopefully he won’t mind the ground. “Colour Squadron won his beginners chase at Killarney the other day. He’s come out of the race well and is in good form. You’d be hoping he’d run well.” Mouse Morris also throws four horses at the race – Rule The World, Horendus Hulabaloo, Ravished and Rogue Angel, who was second in a two-and-a-half-mile handicap chase at Listowel on Sunday. “The ground might be the question mark with Rule The World, but he was running a big race in the Galway Plate when he slipped up,” said the County Tipperary handler. “Horendus Hulabaloo has won around there on soft ground, Ravished won in Limerick on soft ground and Rogue Angel ran a good race there the other day on soft ground.” Ireland’s champion jumps trainer Willie Mullins has a formidable hand with no less than five runners, headed by Galway Plate runner-up The Paparrazi Kid. Alelchi Inois, Indevan, Un Beau Roman and Urano complete his quintet. Press Association